Publications

How abundant are superoxide and hydrogen peroxide in the vasculature lumen, how far can they reach?, Tânia Sousa, Marcos Gouveia, Rui D.M. Salvador, Armindo Salvador, Redox Biology, 58, 102527 (2022).

A multiscale cell-based model of tumor growth for chemotherapy assessment and tumor-targeted therapy through a 3D computational approach, Sahar Jafari Nivlouei, Madjid Soltani, Ebrahim Shirani, Mohammad R. Salimpour, Rui D.M. Travasso, João Carvalho, Cell Proliferation, 55, e13187 (2022).

Mice with type 2 diabetes present significant alterations in their tissue biomechanical properties and histological features, Tânia B. Cruz, Filomena A. Carvalho, Paulo N. Matafome, Raquel A. Soares, Nuno C. Santos, Rui D. Travasso, Maria J. Oliveira, Biomedicines, 10, 57 (2022).

A mathematical model for the dependence of keratin aggregate formation on the quantity of mutant keratin expressed in EGFP-K14 R125P keratinocytes, Marcos Gouveia, Tjaša Sorčan, Špela Zemljič-Jokhadar, Rui D.M. Travasso, Mirjana Liović, PLoS One, 16, e0261227 (2021).

Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine, Rui F. Simões, Rute Pino, Maurício Moreira-Soares, Jaromira Kovarova, Jiri Neuzil, Rui Travasso, Paulo J. Oliveira, Teresa Cunha-Oliveira, Francisco B. Pereira, The FASEB Journal, 35, e22024 (2021).

Intratumoral VEGF nanotrapper reduces gliobastoma vascularization and tumor cell mass, Flávia Sousa, Ana Isabel Costa-Pereira, Andrea Cruz, Fábio Júnio Ferreira, Marcos Gouveia, José Bessa, Bruno Sarmento, Rui DM Travasso, Inês Mendes Pinto, Journal of Controlled Release, 339, 381-390 (2021).

Preface to the JPCM special issue on droplets and vesicles, Marek Cieplak, Rui D M Travasso, J. Phys.:Condens. Matter, 34, 030401 (2021).

A three dimensional computer model of urothelium and bladder cancer initiation, progress and collective invasion, Joao Carvalho, Valeria Lopes, Rui Travasso, Informatics in Medicine Unlocked, 26, 100750 (2021).

Multiscale modeling of tumor growth and angiogenesis: Evaluation of tumor-targeted therapy, Sahar Jafari Nivlouei, M. Soltani, João Carvalho, Rui DM Travasso, Mohammad Reza Salimpour, Ebrahim Shirani, PLoS Computational Biology, 17, e1009081. (2021).

A Bioelectric Model of Carcinogenesis, Including Propagation of Cell Membrane Depolarization and Reversal Therapies, João Carvalho, Scientific Reports, 11, 13607 (2021).

Tumor cell invasiveness in the initial stages of bladder cancer development – A computational study, João Carvalho, Valéria Lopes, Rui DM Travasso, International Journal for Numerical Methods in Biomedical Engineering, 37, e3417 (2021).

Cortical stiffness of keratinocytes measured by lateral indentation with optical tweezers, Špela Zemljič Jokhadar, Biljana Stojković, Marko Vidak, Tjaša Sorčan, Mirjana Liovic, Marcos Gouveia, Rui DM Travasso, Jure Derganc, PLoS One, 15, e0231606 (2020).

Cofilin-1 Is a Mechanosensitive Regulator of Transcription, Catarina Domingues, A. Margarida Geraldo, Sandra Isabel Anjo, André Matos, Cláudio Almeida, Inês Caramelo, José A. Lopes-da-Silva, Artur Paiva, João Carvalho, Ricardo Pires das Neves, Bruno Manadas, Mário Grãos, Frontiers in Cell and Development Biology, 8, 678 (2020).

Keratin dynamics and spatial distribution in wild type and K14 R125P mutant cells – a computational model, Marcos Gouveia, Jure Derganc, Biljana Stojković, Marko Vidak, Špela Zemljič-Jokhadar, Rui Travasso, Mirjana Liović, International Journal of Molecular Sciences, 21, 2596 (2020).

Adhesion modulates cell morphology and migration within dense fibrous networks, Maurício Moreira-Soares, Susana P. Cunha, José Rafael Bordin, Rui D. M. Travasso, J. Phys.:Condens. Matter, 32, 314001 (2020).

Cell Reversal From a Differentiated to a Stem-Like State at Cancer Initiation, João Carvalho, Frontiers in Oncology, 10, 541 (2020).

Notch signaling and taxis mechanisms regulate early stage angiogenesis: A mathematical and computational model, Rocío Vega, Manuel Carretero, Rui D.M. Travasso, Luis L., PLoS Computational Biology, 16, e1006919 (2020).

Resonances in the response of fluidic elastic networks inherent to the cooperation between elasticity and bifurcations, D. Yañez, Rui D.M. Travasso, E. Corvera Poiré, Royal Society Open Science, 6, 190661 (2019).

Soft culture substrates favor stem-like cellular phenotype and facilitate reprogramming of human mesenchymal stem/stromal cells (hMSCs) through mechanotransduction, Heloísa Gerardo, Ana Lima, João Carvalho, João R. D. Ramos, Sofia Couceiro, Rui D. M. Travasso, Ricardo Pires das Neves, Mário Grãos, Scientific Reports, 9, 9086 (2019).

A local uPAR-plasmin-TGFβ1 positive feedback loop in a qualitative computational model of angiogenic sprouting explains the in vitro effect of fibrinogen variants, Sonja E. M. Boas , Joao Carvalho , Marloes van den Broek, Ester M. Weijers, Marie-José Goumans, Pieter Koolwijk, Roeland M. H. Merks, PLoS Computational Biology, 14, e1006239 (2018).

Angiogenic factors produced by hypoxic cells drive anastomoses in sprouting angiogenesis – a computational study, Maurício Moreira Soares, Rita Coimbra, Luís Rebelo, João Carvalho, Rui D.M. Travasso, Scientific Reports, 8, 8726 (2018).

Capillary network formation from dispersed endothelial cells: influence of cell traction, cell adhesion and extracellular matrix rigidity, João R. D. Ramos, Rui Travasso, João Carvalho, Physical Review E, 97, 012408 (2018).

When do redundant fluidic networks outperform non-redundant ones?, Aimée M Torres Rojas, Rui D.M. Travasso, Ignacio Pagonabarraga, Eugenia Corvera Poiré, Europhysics Letters, 117, 64002 (2017).

Localized Redox Relays as a Privileged Mode of Cytoplasmic Hydrogen Peroxide Signaling, Rui D.M. Travasso, Fernando Sampaio dos Aidos, Anahita Bayani, Pedro Abranches, Armindo Salvador, Redox Biology, 12, 233 (2017).

Processing Time Reduction: an Application in Living Human High-Resolution Diffusion Magnetic Resonance Imaging Data, Nicolás F Lori, Augustin Ibañez, Rui Lavrador, Lucia Fonseca, Carlos Santos, Rui Travasso, Artur Pereira, Rosaldo Rossetti, Nuno Sousa, Victor Alves, Journal of Medical Systems, 40, 243 (2016).

Reducing Computation Time by Monte Carlo Method: An Application in Determining Axonal Orientation Distribution Function, Nicolás F Lori, Rui Lavrador, Lucia Fonseca, Carlos Santos, Rui D.M. Travasso, Artur Pereira, Rosaldo Rossetti, Nuno Sousa, Victor Alves, in New Advances in Information Systems and Technologies, Eds. Álvaro Rocha, Ana Maria Correia, Hojjat Adeli, Luis Paulo Reis, Marcelo Mendonça Teixeira, Springer International Publishing (2016)

The Force at the Tip – Modeling Tension and Proliferation in Sprouting Angiogenesis, Patrícia Santos-Oliveira, António Correia, Tiago Rodrigues, Teresa M. Ribeiro-Rodrigues, Paulo Matafome, Juan Carlos Rodríguez-Manzaneque, Raquel Seiça, Henrique Girão, Rui DM Travasso, PLoS Comput Biol, 11, e1004436 (2015).

Obstructions in Vascular Networks: Relation Between Network Morphology and Blood Supply, Aimee Torres, Alejandro M Romero, Ignacio Pagonabarraga, Rui DM Travasso, E. Corvera Poiré, PLoS ONE, 10, e0128111 (2015).

Hypoxia in vascular networks: a complex system approach to unraveling the Diabetes paradox, Yérali Gandica, Tobias Schwarz, Orlando Oliveira, Rui DM Travasso, PLoS ONE, 9, e113165 (2014).

Flow and anastomosis in vascular networks, Joaquín Flores, Alejandro M Romero, Rui DM Travasso, Eugenia Corvera Poiré, J. Theor. Biol., 317, 257 (2013).

Why do protein folding rates correlate with metrics of native topology, Patrícia F.N. Faísca, Rui DM Travasso, Andrea Parisi, Antonio Rey, PLoS ONE, 7, e35599 (2012).

Understanding the Dynamics of Tumor Angiogenesis: a systems biology approach, Maria Margarida Quinas-Guerra, Teresa M Ribeiro-Rodrigues, Juan Carlos Rodríguez-Manzaneque, Rui DM Travasso, in Systems Biology in Cancer Research and Drug Discovery, Ed. A.S. Asfar, Springer (2012).

Tumor angiogenesis and vascular patterning: a mathematical model, Rui DM Travasso, Eugenia Corvera Poiré, Mario Castro, Juan Carlos Rodríguez-Manzaneque, A. Hernández-Machado, PLoS ONE, 6, e19989 (2011).

The phase-field model in tumor growth, Rui DM Travasso, Mario Castro, Joana C.R.E. Oliveira, Philos. Mag., 91, 183 (2011).